RPC
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Analytical Services
  Español (dioxina.com)
     
Dioxins, Furans, and other HRMS Analytical Services    

RPC’s high resolution mass spectrometry (HRMS) laboratory has been serving clients since 1992 and has built a reputation of performing dioxin analysis at the high level of quality required by clients and regulatory agencies. Service is personalized, reliable, confidential, and on-time. Clients include aquaculture growers, feed suppliers, meat and dairy producers, environmental consultants, regulatory authorities, industry and testing laboratories from around the world.

RPC offers high resolution gas chromatography / high resolution mass spectrometry (HRGC/HRMS) analysis of dioxins and furans (PCDD/Fs), dioxin-like PCBs, non-dioxin-like PCBs (also known as marker PCBs or indicator PCBs), all 209 PCB congeners and polybrominated diphenyl ethers (PBDEs) for the monitoring of food, feed, tissue, soil, sediment, ash, water, effuent, ambient air and vegetation, as well as industrial products. Water and effluent are analyzed by HRGC/HRMS for N-nitrosodimethylamine (NDMA).

 

   
DIOXINS & FURANS
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Dioxins and furans are the common terms assigned to a group of 210 chlorinated compounds known as polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs). They are formed as by-products of certain chemical processes and from the inefficient combustion of organic materials. These compounds are extremely stable and persist in the environment for many years. They are strongly lipophilic and bioaccumulate in fatty tissues as they are passed up the food chain. Because PCDD/Fs are believed to cause serious health effects, including cancer and birth defects, at very low levels in humans, low exposure guidelines require trace level analysis.

 
   
OTHER HRMS SERVICES
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Some PCB congeners exhibit toxicological properties similar to those of PCDD/Fs. The World Health Organization (WHO) has classified twelve PCB congeners as "dioxin-like". “Non-dioxin-like PCBs” are six congeners that are the major components in commercial PCB mixtures. They are sometimes used to estimate total PCB concentration. The actual total PCB concentration is the sum of the concentrations of all 209 congeners. Brominated flame retardants (BFRs) are used extensively for fire prevention in a wide range of commercial materials. The polybrominated diphenyl ethers (PBDEs) are an important sub-class of the BFRs. Although toxicological data on PBDEs are limited to date, these compounds are similar to dioxins, furans and dioxin-like PCBs in structure, stability and tendency to bioaccumulate in the food chain.

N-nitrosodimethylamine (NDMA) is a highly carcinogenic byproduct of water treatment which can be present in the environment and in a wide variety of food products.

 

RPC Building

RPC Building

   
     
REFERENCE METHODS
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For Dioxins & Furans:
For Dioxin-like, Marker and all 209 PCBs:
For Polybrominated diphenyl ethers:
For NDMA:
  • Ontario Ministry of Environment (MOE) Method E3291A
   
     
DETECTION LIMITS
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For Dioxins & Furans, Dioxin-like PCBs and PBDEs:
     • <1 part per trillion (ppt) in matrices such as food, feed, soil and sediment
     • <1 part per quadrillion (ppq) in effluent and water samples

For NDMA:
     • 1 part per trillion (ppt) in water

   
     
QUALIFICATIONS
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RPC’s Analytical Services laboratories hold accreditation with the Standards Council of Canada (SCC). The laboratory accreditation program is based on the continued demonstration of performance as evaluated through interlaboratory proficiency testing and laboratory site audits. SCC accredited laboratories are required to conform to the International Laboratory Standard ISO 17025: "General Requirements for the Competence of Testing and Calibration Laboratories".

RPC’s quality management system is registered to ISO 9001:2008.

In addition, the laboratory’s proficiency is demonstrated through successful participation in published interlaboratory studies.

Year
Title
Coordinating Organizations
2016

Interlaboratory Comparison on POPs in Food 2016 (17th Round). Matrices: Sheep Liver, Salmon, Fish Oil

Norwegian Institute of Public
Health Division of Environmental
Medicine (Oslo, Norway)

2016

Interlaboratory Study NCP/AMAP - Phase 10. Matrices: five fish tissues

Ontario Ministry of the Environment (MOE)

2015

Interlaboratory Comparison on POPs in Food 2015 (16th Round).  Matrices: Beef, Salmon and Cheese homogenates

Norwegian Institute of Public
Health Division of Environmental
Medicine (Oslo, Norway)

2015

Interlaboratory Study NCP III - Phase 9.
Matrices: Four fish tissues and two "fish extracts"

Ontario Ministry of the Environment (MOE)

2014

Interlaboratory Study NCP III - Phase 8.
Matrices: Three fish tissues and two "fish extracts"

Ontario Ministry of the Environment (MOE)

2014

Interlaboratory Comparison on POPs in Food 2014 (15th Round).  Matrices: Pork, Herring and Milk homogenates

Norwegian Institute of Public
Health Division of Environmental
Medicine (Oslo, Norway)

2013

Interlaboratory Study NCP III - Phase 7.  Matrices: Three fish tissues and two "fish extracts"

Ontario Ministry of the Environment (MOE)

2013

Interlaboratory Comparison on POPs in Food 2013 (14th Round)
Matrices: Poultry, Crab and Boiled Egg homogenates

Norwegian Institute of Public
Health Division of Environmental
Medicine (Oslo, Norway)

2012

Interlaboratory Comparison on
POPs in Food 2012 (13th Round)
Matrices: Reindeer meat, Halibut and Cod Liver Oil homogenates

Norwegian Institute of Public
Health Division of Environmental
Medicine (Oslo, Norway)

2011

Interlaboratory Study NCP III - Phase 6
Matrices: Four fish tissues and two "fish extracts"

Ontario Ministry of the Environment (MOE)

2011

Interlaboratory Comparison on POPs in Food 2011 (12th Round)
Matrices: Salmon, Mozzarella
chesse and Egg homogenates

Norwegian Institute of Public
Health Division of Environmental
Medicine (Oslo, Norway)
2010

Interlaboratory Study NCP III - Phase 5
Matrices: Three fish tissues and two "fish extracts"

Ontario Ministry of the Environment (MOE)
2010

Interlaboratory Comparison on POPs in Food 2010 (11th Round) Matrices: Pork, Breast milk and Trout homogenates

Norwegian Institute of Public Health Division of Environmental Medicine (Oslo, Norway)
2009

Interlaboratory Comparison on Dioxins in Food 2009 (10th Round) Matrices: Beef, Butteroil and Herring homogenates

Norwegian Institute of Public Health Division of Environmental Medicine (Oslo, Norway)
2008

Interlaboratory Comparison on Dioxins in Food 2008 (9th Round) Matrices: Deer, Cream and Eel homogenates

Norwegian Institute of Public Health Division of Environmental Medicine (Oslo, Norway)
2007

Interlaboratory Comparison on Dioxins in Food 2007(8th Round) Matrices: Salmon and Butter homogenates

Norwegian Institute of Public Health Division of Environmental Medicine (Oslo, Norway)
2006

2006 Second Round International Interlaboratory Study on Sediment, Soil, and Fish Tissue Reference Materials

Cambridge Isotope Laboratories (Andover, MA) & Cerilliant Corporation (Round Rock, TX)

2006

Interlaboratory Comparison on Dioxins in Food 2006 (7th Round) Matrices: Halibut, Egg yolk and Breast milk homogenates

Norwegian Institute of Public Health Division of Environmental Medicine (Oslo, Norway)

2005

Interlaboratory Comparison on Dioxins in Food 2005 (6th Round)
Matrices: Baltic herring, reindeer meat and cod liver oil homogenates

Norwegian Institute of Public Health
Division of Environmental Medicine (Oslo, Norway)

2004
Interlaboratory Comparison on Dioxins in Food 2004 (5th Round) Matrices: trout, palm oil, and chicken homogenates
Norwegian Institute of Public Health Division of Environmental Medicine
(Oslo, Norway)
2003
2003 International Interlaboratory Study on Sediment, Soil, and Fish Tissue Reference Materials
Cambridge Isotope Laboratories & Cerilliant Corporation
2003
Interlaboratory Comparison on Dioxins in Food 2003 (4th Round) Matrices: salmon, turkey and cheese
Norwegian Institute of Public Health Division of Environmental Medicine (Oslo, Norway)
2003
International Intercalibration Studies (8th Round) Matrix: Soil/Sediment
MTM Research Centre
Orebro University, Sweden
Prof. Bert van Bavel (Chair)
1999/2000
MOE Interlaboratory Study 99-2 Dioxins, Dibenzofurans and Dioxin-Like PCBs Matrix: Sediment
MOE Ontario
Quality Management Unit
1997/1998
NIST / ETC Interlaboratory Comparison Study Dioxins in SRM 1649a (Urban Dust/Organics) & SRM 1944 (NY/NJ Waterway Sediment)
Analytical Chemistry Division National Institute of Standards and Technology (NIST) & Environmental Technology Centre (ETC) Environment Canada
1995
Environment Canada Certified Reference Materials (CRM) Study
Matrices: reference sediments EC-2 & EC-3
Aquatic Ecosystem Protection Branch National Water Research Institute (NWRI) Environment Canada
1994
CAEAL Dioxin/Furan Interlaboratory Comparison Study
Matrices: Ash and Sludge extracts
Canadian Association for Environmental Analytical Laboratories (CAEAL) and Environment Canada
1994
Canadian Environmental Protection Act (CEPA) National Interlaboratory Comparison Study (CP-4): Analysis of Dioxins and Furans in Sediment Extracts
Aquatic Ecosystem Protection Branch National Water Research Institute (NWRI) Environment Canada
1992
National Dioxin Interlaboratory QA Study No. 5 Analysis of Dioxins and Furans in Sediments
Research and Applications Branch National Water Research Institute (NWRI) Environment Canada
   
     
REPORTING
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Results are reported on an individual congener as well as a toxic equivalent (TEQ) basis. Final reports are available by request in English, French or Spanish and can be customized to client specifications. Electronic data in spreadsheet format can also be provided.

   
     
TURNAROUND TIMES
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RPC's turnaround times are generally 20 business days but may vary depending on workload. In priority situations, RPC can offer more rapid turnaround-times (surcharges will apply).

   
     
CONTACT
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If you have questions of a technical nature, please e-mail us at info@dioxinlab.com.

For a price quotation please contact us by telephone (506-460-5671), by email at info@dioxinlab.com.

Hablamos castellano. Para más información visítenos a nuestra página web: www.dioxina.com

   
     
ADDITIONAL RESOURCES
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Dioxin & Furan Analysis Info Sheet (PDF)

   
     
RELATED LINKS
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RPC (Research and Productivity Council)
Environment Canada
Canadian Food Inspection Agency (CFIA)
United States Environmental Protection Agency
USEPA - Dioxin and Related Compounds
World Health Organization - Dioxin Information
FERA - Legislation and Reference Sources
EU Regulation No. 589/2014

RG-8 Regulatory Guideance - Section 2: Action Levels for Dioxins, Furans, Dioxin-like polychlorinated biphenyls (PCBs) and Total PCBs in Livestock Feed